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Literature summary for 1.14.19.1 extracted from

  • Flowers, M.T.; Ntambi, J.M.
    Stearoyl-CoA desaturase and its relation to high-carbohydrate diets and obesity (2009), Biochim. Biophys. Acta, 1791, 85-91.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.14.19.1

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
adipose tissue
-
 Mus musculus
-
liver
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
palmitoyl-CoA + NADH + H+ + O2
-
 Mus musculus palmitoleoyl-CoA + NAD+ + H2O
-
 ?
stearoyl-CoA + NADH + H+ + O2
-
 Mus musculus oleoyl-CoA + NAD+ + H2O
-
 ?

Synonyms

Synonyms Comment Organism
SCD1
-
 Mus musculus
stearoyl-CoA desaturase
-
 Mus musculus
stearoyl-coenzyme A desaturase-1
-
 Mus musculus

Cofactor

Cofactor Comment Organism Structure
NADH
-
 Mus musculus

Expression

Organism Comment Expression
Mus musculus intracerebroventricular glucose administration strongly decreases hepatic Scd1 down
Mus musculus dietary saturated fat strongly induces Scd1 expression up

General Information

General Information Comment Organism
physiological function mice lacking Scd1 are protected from obesity and insulin resistance and are characterized by decreased fatty acid synthesis and increased fatty acid oxidation Mus musculus