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Literature summary for 1.14.19.1 extracted from
- Development of a novel LC/MS method to quantitate cellular stearoyl-CoA desaturase activity (2008), Anal. Chim. Acta, 627, 99-104.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Sterculic acid | inhibits the enzyme activity in a dose dependent manner with a calculated EC50 of 247 nM | Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| Hep-G2 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| palmitoyl-CoA + NADH + H+ + O2 | 13% conversion | Homo sapiens | palmitoleoyl-CoA + NAD+ + H2O | - |
? | |
| stearoyl-CoA + NADH + H+ + O2 | 45% conversion | Homo sapiens | oleoyl-CoA + NAD+ + H2O | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| SCD1 | - |
Homo sapiens |
| stearoyl-CoA desaturase 1 | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADH | - |
Homo sapiens | |
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Release 2023.1 (January 2023)
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