Inhibitors | Comment | Organism | Structure |
---|---|---|---|
cis-10,trans-12-conjugated linoleic acid | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
arterial endothelial cell | - |
Homo sapiens | - |
coronary artery smooth muscle cell line | - |
Homo sapiens | - |
HAEC cell | - |
Homo sapiens | - |
HEK-293 cell | - |
Homo sapiens | - |
Hep-G2 cell | - |
Homo sapiens | - |
myotube | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
SCD-1 | - |
Homo sapiens |
stearoyl-CoA desaturase-1 | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | SCD-1 is not upregulated in HAEC cells upon palmitate treatment | additional information |
Homo sapiens | SCD-1 expression is about 2fold upregulated in coronary artery smooth muscle cells, myotubes, and Hep-G2 cells at 0.5 mM palmitate, SCD-1 is upregulated using 0.01 mM TO-901317 in HAEC cells, inhibition of SCD-1 with cis-10,trans-12-conjugated linoleic acid blocks the upregulating effect of TO-901317 | up |