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Literature summary for 1.14.19.1 extracted from

  • Biddinger, S.B.; Miyazaki, M.; Boucher, J.; Ntambi, J.M.; Kahn, C.R.
    Leptin suppresses stearoyl-CoA desaturase 1 by mechanisms independent of insulin and sterol regulatory element-binding protein-1c (2006), Diabetes, 55, 2032-2041.
    View publication on PubMed
Search for more literature for 1.14.19.1

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Mus musculus
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
additional information
-
 SCD protein undetectable in 24 microg/day leptin-treated ob/ob mice with or without exogenous insulin treatment Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
 ob/ob mice
-

Source Tissue

Source Tissue Comment Organism Textmining
liver 24 microg/day leptin treatment for 4 days with or without exogenous insulin treatment of ob/ob mice suppresses mRNA, SCD protein undetectable in leptin-treated ob/ob mice with or without exogenous insulin treatment Mus musculus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 10fold suppression in 24 microg/day leptin-treated ob/ob mice with or without exogenous insulin treatment Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
stearoyl-CoA + AH2 + O2
-
 Mus musculus oleoyl-CoA + A + H2O
-
 ?

Synonyms

Synonyms Comment Organism
SCD1
-
 Mus musculus