Any feedback?
Literature summary for 1.14.19.1 extracted from
- Properties of rat liver microsomal stearoyl-coenzyme A desaturase (1977), Biochem. J., 161, 431-437.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| bovine serum albumin | stimulates activity in the microsomal fraction | Rattus norvegicus | |
| cytochrome b5 reductase | NADH-specific, required, EC 1.6.2.2 | Rattus norvegicus | |
| protein | basic cytoplasmic protein from rat liver stimulates activity in crude extract, no activity of partially purified enzyme | Rattus norvegicus |  |
| stearoyl-CoA-binding protein | stimulates activity in the crude microsomal fraction | Rattus norvegicus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| endoplasmic reticulum | bound | Rattus norvegicus | 5783 | - |
| microsome | - |
Rattus norvegicus | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
Colworth-Wistar, male | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partially | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.0315 | - |
- |
Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | specific for C14-C19 fatty acyl-CoA substrates | Rattus norvegicus | ? | - |
? | |
| myristoyl-CoA + AH2 + O2 | - |
Rattus norvegicus | ? | - |
? | |
| nonadecanoyl-CoA + NADH + O2 | - |
Rattus norvegicus | ? | - |
? | |
| palmitoyl-CoA + NADH + O2 | - |
Rattus norvegicus | palmitoleoyl-CoA + NAD+ + H2O | - |
? | |
| stearoyl-CoA + NADH + O2 | maximal activity | Rattus norvegicus | oleoyl-CoA + NAD+ + H2O | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
assay at | Rattus norvegicus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
assay at | Rattus norvegicus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| cytochrome b5 | required | Rattus norvegicus | |
| NADH | - |
Rattus norvegicus | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
