Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(2E)-3-(3,4-dihydroxyphenyl)-N-(2-phenylethyl)prop-2-enamide | - |
Agaricus bisporus | |
(2E)-3-(3,4-dihydroxyphenyl)-N-(4-hydroxybenzyl)prop-2-enamide | - |
Agaricus bisporus | |
(2E)-3-(3,4-dihydroxyphenyl)-N-[2-(3,4-dihydroxyphenyl)ethyl]prop-2-enamide | - |
Agaricus bisporus | |
(2E)-3-(3,4-dihydroxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]prop-2-enamide | - |
Agaricus bisporus | |
(2E)-3-(3,4-dihydroxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]prop-2-enamide | - |
Agaricus bisporus | |
(2E)-3-(4-chlorophenyl)-N-[2-(4-chlorophenyl)ethyl]prop-2-enamide | - |
Agaricus bisporus | |
(2E)-3-(4-hydroxyphenyl)-N-(2-phenylethyl)prop-2-enamide | strong tyrosinase inhibitory potential | Agaricus bisporus | |
(2E)-3-(4-methoxyphenyl)-N-(1-phenylethyl)prop-2-enamide | - |
Agaricus bisporus | |
(2E)-3-(4-methoxyphenyl)-N-(2-phenylethyl)prop-2-enamide | - |
Agaricus bisporus | |
(2E)-3-phenyl-N-(1-phenylethyl)prop-2-enamide | - |
Agaricus bisporus | |
(2E)-3-phenyl-N-(2-phenylethyl)prop-2-enamide | - |
Agaricus bisporus | |
(2E)-N-(3,4-dihydroxybenzyl)-3-(3,4-dihydroxyphenyl)prop-2-enamide | - |
Agaricus bisporus | |
(2E)-N-(4-chlorobenzyl)-3-phenylprop-2-enamide | - |
Agaricus bisporus | |
(2E)-N-benzyl-3-(3,4-dihydroxyphenyl)prop-2-enamide | - |
Agaricus bisporus | |
(2E)-N-benzyl-3-(4-hydroxyphenyl)prop-2-enamide | strong tyrosinase inhibitory potential | Agaricus bisporus | |
(2E)-N-benzyl-3-(4-methoxyphenyl)prop-2-enamide | - |
Agaricus bisporus | |
(2E)-N-benzyl-3-phenylprop-2-enamide | - |
Agaricus bisporus | |
(2E)-N-[2-(4-chlorophenyl)ethyl]-3-(4-hydroxyphenyl)prop-2-enamide | - |
Agaricus bisporus | |
(2E)-N-[2-(4-chlorophenyl)ethyl]-3-phenylprop-2-enamide | - |
Agaricus bisporus | |
3-hydroxycinnamic acid | - |
Agaricus bisporus | |
caffeic acid | i.e. 3,4-dihydroxycinnamic acid | Agaricus bisporus | |
Cinnamic acid | - |
Agaricus bisporus | |
hydroquinone | - |
Agaricus bisporus | |
kojic acid | - |
Agaricus bisporus | |
p-coumaric acid | - |
Agaricus bisporus | |
phenylethylamide | - |
Agaricus bisporus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Agaricus bisporus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-tyrosine + O2 | - |
Agaricus bisporus | dopaquinone + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
tyrosinase | - |
Agaricus bisporus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.028 | - |
- |
Agaricus bisporus | (2E)-N-benzyl-3-(4-hydroxyphenyl)prop-2-enamide | |
0.03 | - |
- |
Agaricus bisporus | (2E)-3-(4-hydroxyphenyl)-N-(2-phenylethyl)prop-2-enamide | |
0.037 | - |
- |
Agaricus bisporus | hydroquinone | |
0.075 | - |
- |
Agaricus bisporus | kojic acid | |
0.1 | - |
IC50 above 0.1 mM | Agaricus bisporus | (2E)-3-phenyl-N-(2-phenylethyl)prop-2-enamide | |
0.1 | - |
IC50 above 0.1 mM | Agaricus bisporus | (2E)-N-[2-(4-chlorophenyl)ethyl]-3-(4-hydroxyphenyl)prop-2-enamide | |
0.1 | - |
IC50 above 0.1 mM | Agaricus bisporus | (2E)-N-benzyl-3-phenylprop-2-enamide | |
0.1 | - |
IC50 above 0.1 mM | Agaricus bisporus | (2E)-N-(4-chlorobenzyl)-3-phenylprop-2-enamide | |
0.1 | - |
IC50 above 0.1 mM | Agaricus bisporus | (2E)-3-phenyl-N-(1-phenylethyl)prop-2-enamide | |
0.2 | - |
- |
Agaricus bisporus | p-coumaric acid | |
0.25 | - |
- |
Agaricus bisporus | (2E)-3-(3,4-dihydroxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]prop-2-enamide | |
0.25 | - |
- |
Agaricus bisporus | (2E)-N-benzyl-3-(3,4-dihydroxyphenyl)prop-2-enamide | |
0.35 | - |
- |
Agaricus bisporus | (2E)-3-(3,4-dihydroxyphenyl)-N-(4-hydroxybenzyl)prop-2-enamide | |
0.35 | - |
- |
Agaricus bisporus | (2E)-N-(3,4-dihydroxybenzyl)-3-(3,4-dihydroxyphenyl)prop-2-enamide | |
0.4 | - |
- |
Agaricus bisporus | caffeic acid | |
0.6 | - |
- |
Agaricus bisporus | (2E)-3-(3,4-dihydroxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]prop-2-enamide | |
1 | - |
IC50 above 1 mM | Agaricus bisporus | Cinnamic acid | |
1 | - |
IC50 above 1 mM | Agaricus bisporus | 3-hydroxycinnamic acid | |
1 | - |
IC50 above 1 mM | Agaricus bisporus | (2E)-3-(3,4-dihydroxyphenyl)-N-[2-(3,4-dihydroxyphenyl)ethyl]prop-2-enamide | |
1 | - |
IC50 above 1 mM | Agaricus bisporus | (2E)-3-(3,4-dihydroxyphenyl)-N-(2-phenylethyl)prop-2-enamide | |
1 | - |
IC50 above 1 mM | Agaricus bisporus | (2E)-3-(4-methoxyphenyl)-N-(2-phenylethyl)prop-2-enamide | |
1 | - |
IC50 above 1 mM | Agaricus bisporus | (2E)-N-[2-(4-chlorophenyl)ethyl]-3-phenylprop-2-enamide | |
1 | - |
IC50 above 1 mM | Agaricus bisporus | (2E)-3-(4-chlorophenyl)-N-[2-(4-chlorophenyl)ethyl]prop-2-enamide | |
1 | - |
IC50 above 1 mM | Agaricus bisporus | (2E)-N-benzyl-3-(4-methoxyphenyl)prop-2-enamide | |
1 | - |
IC50 above 1 mM | Agaricus bisporus | (2E)-3-(4-methoxyphenyl)-N-(1-phenylethyl)prop-2-enamide |