Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-hexylresorcinol | - |
Agaricus bisporus | |
ammonium tetramolybdate | - |
Agaricus bisporus | |
esculetin | - |
Agaricus bisporus | |
kojic acid | - |
Agaricus bisporus | |
Methimazole | - |
Agaricus bisporus | |
Salicylhydroxamic acid | - |
Agaricus bisporus | |
tropolone | - |
Agaricus bisporus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.25 | - |
Dopa | Sigma mushroom tyrosinase (SMT, crude powder, lot 105k7026) | Agaricus bisporus | |
0.46 | - |
Dopa | Worthington mushroom tyrosinase (WMT, crude powder, lot 33H6588Q) | Agaricus bisporus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
45000 | - |
x * 45000, SDS-PAGE | Agaricus bisporus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Agaricus bisporus | O42713 | - |
- |
Purification (Comment) | Organism |
---|---|
partial purification of tyrosinase | Agaricus bisporus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
commercial preparation | Worthington mushroom tyrosinase (WMT, crude powder, lot 33H6588Q) and Sigma mushroom tyrosinase (SMT, crude powder, lot 105k7026) | Agaricus bisporus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
498 | - |
Worthington mushroom tyrosinase (WMT, crude powder, lot 33H6588Q) (units/mg of powder), WMT and SMT show different levels of tyrosinase activity per milligram of powder | Agaricus bisporus |
1700 | - |
Sigma mushroom tyrosinase (SMT, crude powder, lot 105k7026) (units/mg of powder), WMT and SMT show different levels of tyrosinase activity per milligram of powder | Agaricus bisporus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-dopa + 1/2 O2 | - |
Agaricus bisporus | L-dopaquinone + H2O | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | x * 45000, SDS-PAGE | Agaricus bisporus |
Synonyms | Comment | Organism |
---|---|---|
monophenol, o-diphenol:oxygen oxido-reductase | - |
Agaricus bisporus |
PPO2 | - |
Agaricus bisporus |
tyrosinase | - |
Agaricus bisporus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0008 | - |
Worthington mushroom tyrosinase (WMT, crude powder, lot 33H6588Q) | Agaricus bisporus | Salicylhydroxamic acid | |
0.0009 | - |
Sigma mushroom tyrosinase (SMT, partially purified) | Agaricus bisporus | Salicylhydroxamic acid | |
0.0012 | - |
Sigma mushroom tyrosinase (SMT, crude powder, lot 105k7026) | Agaricus bisporus | Salicylhydroxamic acid | |
0.0013 | - |
Sigma mushroom tyrosinase (SMT, crude powder, lot 105k7026) | Agaricus bisporus | tropolone | |
0.0017 | - |
Sigma mushroom tyrosinase (SMT, partially purified) | Agaricus bisporus | tropolone | |
0.0025 | - |
Sigma mushroom tyrosinase (SMT, partially purified) | Agaricus bisporus | 4-hexylresorcinol | |
0.0075 | - |
Sigma mushroom tyrosinase (SMT, partially purified) | Agaricus bisporus | ammonium tetramolybdate | |
0.018 | - |
Sigma mushroom tyrosinase (SMT, crude powder, lot 105k7026) | Agaricus bisporus | 4-hexylresorcinol | |
0.025 | - |
Sigma mushroom tyrosinase (SMT, partially purified) | Agaricus bisporus | kojic acid | |
0.028 | - |
Sigma mushroom tyrosinase (SMT, crude powder, lot 105k7026) | Agaricus bisporus | ammonium tetramolybdate | |
0.03 | - |
Sigma mushroom tyrosinase (SMT, crude powder, lot 105k7026) | Agaricus bisporus | kojic acid | |
0.04 | - |
Sigma mushroom tyrosinase (SMT, crude powder, lot 105k7026) | Agaricus bisporus | Methimazole | |
0.045 | - |
Worthington mushroom tyrosinase (WMT, crude powder, lot 33H6588Q) | Agaricus bisporus | kojic acid | |
0.047 | - |
Sigma mushroom tyrosinase (SMT, partially purified) | Agaricus bisporus | Methimazole | |
0.21 | - |
Worthington mushroom tyrosinase (WMT, crude powder, lot 33H6588Q) | Agaricus bisporus | esculetin | |
0.225 | - |
Sigma mushroom tyrosinase (SMT, crude powder, lot 105k7026) | Agaricus bisporus | esculetin |