Application | Comment | Organism |
---|---|---|
additional information | phenoloxidase inhibitors are increasingly used in medicinal and cosmetic products | Pieris rapae |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-dodecylresorcinol | reversible and competitive inhibition, IC50: 0.00112 mM | Pieris rapae | |
4-hexylresorcinol | reversible and competitive inhibition, IC50: 0.00150 mM | Pieris rapae |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.8 | - |
L-Dopa | pH 6.8, 37°C | Pieris rapae |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Cu2+ | a copper containing bifunctional enzyme | Pieris rapae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-DOPA + O2 | Pieris rapae | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pieris rapae | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
larva | - |
Pieris rapae | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-DOPA + O2 | - |
Pieris rapae | ? | - |
? | |
L-DOPA + O2 | i.e. L-3, 4-dihydroxyphenylalanine | Pieris rapae | ? | - |
? | |
additional information | the enzyme catalyzes the hydroxylation of monophenols to o-diphenols, monophenolase activity EC 1.14.18.1, and the oxidation of the o-diphenols to o-quinones, diphenolase activity EC 1.10.3.1, cross-reaction analysis, overview | Pieris rapae | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
More | cf. EC 1.10.3.1 | Pieris rapae |
phenoloxidase | - |
Pieris rapae |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
42 | - |
- |
Pieris rapae |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
partially purified enzyme, stable up to | Pieris rapae |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
- |
Pieris rapae |
pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|
6.5 | 7.4 | partially purified enzyme, stable at | Pieris rapae |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | inhibition kinetics | Pieris rapae | |
0.00047 | - |
4-dodecylresorcinol | pH 6.8, 37°C | Pieris rapae | |
0.0005 | - |
4-hexylresorcinol | pH 6.8, 37°C | Pieris rapae |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00112 | - |
reversible and competitive inhibition, IC50: 0.00112 mM | Pieris rapae | 4-dodecylresorcinol | |
0.0015 | - |
reversible and competitive inhibition, IC50: 0.00150 mM | Pieris rapae | cyclohex-2-ene-1-carbonyl-CoA |