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Literature summary for 1.14.17.4 extracted from

  • Brisson, L.; El Bakkali-Taheri, N.; Giorgi, M.; Fadel, A.; Kaizer, J.; Reglier, M.; Tron, T.; Ajandouz, e.l..H.; Simaan, A.J.
    1-Aminocyclopropane-1-carboxylic acid oxidase: insight into cofactor binding from experimental and theoretical studies (2012), J. Biol. Inorg. Chem., 17, 939-949.
    View publication on PubMed
Search for more literature for 1.14.17.4

Activating Compound

Activating Compound Comment Organism Structure
bicarbonate the enzyme requires the presence of CO2 or bicarbonate for activity Solanum lycopersicum

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Solanum lycopersicum

Inhibitors

Inhibitors Comment Organism Structure
(1-amino-1-methyl)ethylphosphonic acid competitive inhibitor versus both 1-aminocyclopropane-1-carboxylate and bicarbonate Solanum lycopersicum
1-aminocyclopropane-1-phosphonic acid competitive inhibitor versus both 1-aminocyclopropane-1-carboxylate and bicarbonate Solanum lycopersicum

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.15
-
 1-aminocyclopropane-1-carboxylate in 50 mM MOPS, pH 7.0, at 29°C Solanum lycopersicum
2.7
-
 ascorbate in 50 mM MOPS, pH 7.0, at 29°C Solanum lycopersicum

Metals/Ions

Metals/Ions Comment Organism Structure
Fe2+ a nonheme Fe(II)-containing enzyme Solanum lycopersicum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1-aminocyclopropane-1-carboxylate + ascorbate + O2 + H+ Solanum lycopersicum
-
 ethylene + cyanide + dehydroascorbate + CO2 + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Solanum lycopersicum
-
-
-

Purification (Commentary)

Purification (Comment) Organism
DEAE Sepharose resin column chromatography Solanum lycopersicum

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-aminocyclopropane-1-carboxylate + ascorbate + O2 + H+
-
 Solanum lycopersicum ethylene + cyanide + dehydroascorbate + CO2 + H2O
-
 ?

Synonyms

Synonyms Comment Organism
1-aminocyclopropane-1-carboxylic acid oxidase
-
 Solanum lycopersicum
ACC oxidase
-
 Solanum lycopersicum
ACCO
-
 Solanum lycopersicum

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.19
-
 1-aminocyclopropane-1-carboxylate in 50 mM MOPS, pH 7.0, at 29°C Solanum lycopersicum
0.2
-
 ascorbate in 50 mM MOPS, pH 7.0, at 29°C Solanum lycopersicum

Cofactor

Cofactor Comment Organism Structure
ascorbate
-
 Solanum lycopersicum

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.5
-
 1-aminocyclopropane-1-phosphonic acid in 50 mM MOPS, pH 7.0, at 29°C Solanum lycopersicum
2.3
-
 (1-amino-1-methyl)ethylphosphonic acid in 50 mM MOPS, pH 7.0, at 29°C Solanum lycopersicum