Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(decanoylsulfanyl)acetic acid | - |
Homo sapiens | |
(dodecanoyloxy)acetic acid | - |
Homo sapiens | |
decanoyloxyacetic acid | - |
Homo sapiens | |
[(phenylacetyl)oxy]acetic acid | - |
Homo sapiens | |
[(phenylacetyl)sulfanyl]acetic acid | - |
Homo sapiens | |
[[(2S)-2-(acetylamino)-3-phenylpropanoyl]oxy]acetic acid | - |
Homo sapiens | |
[[(2S)-2-(acetylamino)-3-phenylpropanoyl]sulfanyl]acetic acid | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.015 | - |
N-acetyl-L-phenylalanylglycine | pH and temperature not specified in the publication | Homo sapiens | |
0.2 | - |
N-decanoylglycine | pH and temperature not specified in the publication | Homo sapiens | |
0.33 | - |
N-(Phenylacetyl)glycine | pH and temperature not specified in the publication | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
peptidylglycine + ascorbate + O2 | Homo sapiens | - |
peptidyl(2-hydroxyglycine) + dehydroascorbate + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
NCI-H889 cell | - |
Homo sapiens | - |
small cell lung cancer cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-(phenylacetyl)glycine + ascorbate + O2 | - |
Homo sapiens | ? + dehydroascorbate + H2O | - |
? | |
N-acetyl-L-phenylalanylglycine + ascorbate + O2 | - |
Homo sapiens | ? + dehydroascorbate + H2O | - |
? | |
N-decanoylglycine + ascorbate + O2 | - |
Homo sapiens | ? | - |
? | |
peptidylglycine + ascorbate + O2 | - |
Homo sapiens | peptidyl(2-hydroxyglycine) + dehydroascorbate + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PAM | - |
Homo sapiens |
peptidylglycine alpha-amidating monooxygenase | - |
Homo sapiens |
peptidylglycine alpha-hydroxylating monooxygenase | subunit of bifunctional peptidylglycine alpha-amidating monooxygenase (PAM) | Homo sapiens |
PHM | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ascorbate | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00005 | - |
pH and temperature not specified in the publication | Homo sapiens | decanoyloxyacetic acid | |
0.00006 | - |
pH and temperature not specified in the publication | Homo sapiens | (dodecanoyloxy)acetic acid | |
0.002 | - |
pH and temperature not specified in the publication | Homo sapiens | [(phenylacetyl)oxy]acetic acid | |
0.006 | - |
pH and temperature not specified in the publication | Homo sapiens | [[(2S)-2-(acetylamino)-3-phenylpropanoyl]oxy]acetic acid | |
0.007 | - |
pH and temperature not specified in the publication | Homo sapiens | (decanoylsulfanyl)acetic acid | |
0.045 | - |
pH and temperature not specified in the publication | Homo sapiens | [(phenylacetyl)sulfanyl]acetic acid | |
0.045 | - |
pH and temperature not specified in the publication | Homo sapiens | [[(2S)-2-(acetylamino)-3-phenylpropanoyl]sulfanyl]acetic acid |