Literature summary for 1.14.16.4 extracted from

Rotberg, B.; Kronenberg, S.; Carmel, M.; Frisch, A.; Brent, D.; Zalsman, G.; Apter, A.; Weizman, A.
Additive effects of 5-HTTLPR (serotonin transporter) and tryptophan hydroxylase 2 G-703T gene polymorphisms on the clinical response to citalopram among children and adolescents with depression and anxiety disorders (2013), J. Child Adolesc. Psychopharmacol., 23, 117-122.

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Application

Application	Comment	Organism
medicine	the serotonin transporter gene-linked promoter region 5-HTTLPR and tryptophan hydroxylase-2 genes act in concert to modulate the clinical response to citalopram among children and adolescents with depression and/or anxiety disorders	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Synonyms

Synonyms	Comment	Organism
TPH2	-	Homo sapiens
tryptophan hydroxylase 2	-	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
tetrahydrobiopterin	-	Homo sapiens

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Release 2023.1 (January 2023)