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Literature summary for 1.14.16.4 extracted from

  • Zhang, X.; Beaulieu, J.M.; Sotnikova, T.D.; Gainetdinov, R.R.; Caron, M.G.
    Tryptophan hydroxylase-2 controls brain serotonin synthesis (2004), Science, 305, 217.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-tryptophan + tetrahydropteridine + O2 Mus musculus tryptophan hydroxylase-2 controls brain serotonin synthesis 5-hydroxy-L-tryptophan + dihydropteridine + H2O
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?

Organism

Organism UniProt Comment Textmining
Mus musculus Q8CGV2
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-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-tryptophan + tetrahydropteridine + O2 tryptophan hydroxylase-2 controls brain serotonin synthesis Mus musculus 5-hydroxy-L-tryptophan + dihydropteridine + H2O
-
?

Synonyms

Synonyms Comment Organism
tryptophan hydroxylase-2
-
Mus musculus