Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.14.16.2 extracted from

  • Chen, Y.; Lian, Y.; Ma, Y.; Wu, C.; Zheng, Y.; Xie, N.
    The expression and significance of tyrosine hydroxylase in the brain tissue of Parkinsons disease rats (2017), Exp. Ther. Med., 14, 4813-4816 .
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-tyrosine + tetrahydrobiopterin + O2 Rattus norvegicus
-
L-dopa + 4a-hydroxytetrahydrobiopterin + H2O
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-tyrosine + tetrahydrobiopterin + O2
-
Rattus norvegicus L-dopa + 4a-hydroxytetrahydrobiopterin + H2O
-
?

Synonyms

Synonyms Comment Organism
tyrosine hydroxylase
-
Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus compared with the control group, the expression of enzyme mRNA in both sides of the brain tissue in Parkinson rats decreases during 8 weeks, and the expression of mRNA in the injured brain tissue is significantly lower than that in normal rats down