Activating Compound | Comment | Organism | Structure |
---|---|---|---|
7,12-dimethylbenz[a]anthracene | tyrosine hydroxylase activity increases in the rat heart treated with 7,12-dimethylbenz[a]anthracene | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | the tyrosine hydroxylase activity decreases in the hearts of rats administrated 7,12-dimethylbenz[a]anthracene + 1-isopropyl-3-methylbenzimidazole-2-selenone and 7,12-dimethylbenz[a]anthracene + 1,3-di-p-methoxybenzylpyrimidine-2-selenone according to 7,12-dimethylbenz[a]anthracene group | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-tyrosine + 6-methyl-tetrahydrobiopterin + O2 | - |
Rattus norvegicus | 3,4-dihydroxy-L-phenylalanine + 6-methyl-4a-hydroxytetrahydrobiopterin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
tyrosine hydroxylase | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
tetrahydrobiopterin | - |
Rattus norvegicus |