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Literature summary for 1.14.16.2 extracted from

  • Talas, Z.S.; Ozdemir, I.; Gok, Y.; Ates, B.; Yilmaz, I.
    Role of selenium compounds on tyrosine hydroxylase activity, adrenomedullin and total RNA levels in hearts of rats (2009), Regul. Pept., 159, 137-141.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
7,12-dimethylbenz[a]anthracene tyrosine hydroxylase activity increases in the rat heart treated with 7,12-dimethylbenz[a]anthracene Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
additional information the tyrosine hydroxylase activity decreases in the hearts of rats administrated 7,12-dimethylbenz[a]anthracene + 1-isopropyl-3-methylbenzimidazole-2-selenone and 7,12-dimethylbenz[a]anthracene + 1,3-di-p-methoxybenzylpyrimidine-2-selenone according to 7,12-dimethylbenz[a]anthracene group Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-tyrosine + 6-methyl-tetrahydrobiopterin + O2
-
Rattus norvegicus 3,4-dihydroxy-L-phenylalanine + 6-methyl-4a-hydroxytetrahydrobiopterin
-
?

Synonyms

Synonyms Comment Organism
tyrosine hydroxylase
-
Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
tetrahydrobiopterin
-
Rattus norvegicus