Activating Compound | Comment | Organism | Structure |
---|---|---|---|
1,4-dithiothreitol | 48% activity without dithiotreitol | Drosophila melanogaster |
Cloned (Comment) | Organism |
---|---|
expression Escherichia coli BL21(DE33) | Drosophila melanogaster |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3-iodotyrosine | - |
Drosophila melanogaster | |
alpha-methyl-p-tyrosine | - |
Drosophila melanogaster | |
dopamine | - |
Drosophila melanogaster | |
epinephrine | - |
Drosophila melanogaster | |
L-Dopa | - |
Drosophila melanogaster | |
L-phenylalanine | - |
Drosophila melanogaster | |
norepinephrine | - |
Drosophila melanogaster |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Fe2+ | activating | Drosophila melanogaster |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Drosophila melanogaster | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | the enzyme is activated by cAMP-dependent protein kinase in vitro | Drosophila melanogaster |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cell culture | - |
Drosophila melanogaster | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-tyrosine + 6,7-dimethyl-2-amino-4-hydroxy-5,6,7,8-tetrahydopteridine + O2 | - |
Drosophila melanogaster | 3,4-dihydroxyphenylalanine + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TH | - |
Drosophila melanogaster |
tyrosine hydroxylase | - |
Drosophila melanogaster |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
31 | - |
- |
Drosophila melanogaster |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
6,7-dimethyl-2-amino-4-hydroxy-5,6,7,8-tetrahydopteridine | strictly requirred | Drosophila melanogaster |