Inhibitors | Comment | Organism | Structure |
---|---|---|---|
deferoxamine | 5 mM, 1% residual activity | Rattus norvegicus | |
L-methionine | 5 mM, 55% residual activity with substrate L-phenylalanine | Rattus norvegicus | |
L-phenylalanine | competitive | Rattus norvegicus | |
S-carboxymethyl-L-cysteine | competitive to L-phenylalanine, 5 mM, 74% residual activity with substrate L-phenylalanine | Rattus norvegicus | |
S-methyl-L-cysteine | competitive to L-phenylalanine, 5 mM, 89% residual activity with substrate L-phenylalanine | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00936 | - |
tetrahydrobiopterin | pH 6.8, 37°C, cosubstrate L-phenylalanine | Rattus norvegicus | |
0.26 | - |
L-phenylalanine | pH 6.8, 37°C | Rattus norvegicus | |
14.73 | - |
S-carboxymethyl-L-cysteine | pH 6.8, 37°C | Rattus norvegicus | |
43.25 | - |
S-methyl-L-cysteine | pH 6.8, 37°C | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Rattus norvegicus | 5829 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Iron | - |
Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
Wistar | - |
Rattus norvegicus Wistar | - |
Wistar | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-phenylalanine + tetrahydrobiopterin + O2 | - |
Rattus norvegicus | L-tyrosine + dihydrobiopterin + H2O | - |
? | |
L-phenylalanine + tetrahydrobiopterin + O2 | - |
Rattus norvegicus Wistar | L-tyrosine + dihydrobiopterin + H2O | - |
? | |
S-carboxymethyl-L-cysteine + tetrahydrobiopterin + O2 | - |
Rattus norvegicus | S-carboxymethyl-L-cysteine S-oxide + dihydrobiopterin + H2O | - |
? | |
S-carboxymethyl-L-cysteine + tetrahydrobiopterin + O2 | - |
Rattus norvegicus Wistar | S-carboxymethyl-L-cysteine S-oxide + dihydrobiopterin + H2O | - |
? | |
S-methyl-L-cysteine + tetrahydrobiopterin + O2 | - |
Rattus norvegicus | S-methyl-L-cysteine S-oxide + dihydrobiopterin + H2O | - |
? | |
S-methyl-L-cysteine + tetrahydrobiopterin + O2 | - |
Rattus norvegicus Wistar | S-methyl-L-cysteine S-oxide + dihydrobiopterin + H2O | - |
? |