Any feedback?
Literature summary for 1.14.15.6 extracted from
- Studies of granulosa cell maturation in dominant and subordinate bovine follicles: novel extracellular matrix focimatrix is co-ordinately regulated with cholesterol side-chain cleavage CYP11A1 (2009), Reproduction, 137, 825-834.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| ovarian follicle | granulosa cell | Bos taurus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| cholesterol side-chain cleavage enzyme | - |
Bos taurus |
| CYP11A1 | - |
Bos taurus |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Bos taurus | mRNA levels for CYP11A1 are significantly lower in subordinate follicles in comparison to dominant follicles and this effect is maintained following adjustment for follicle size | down |
| Bos taurus | CYP11A1 is elevated in dominant follicles. CYP11A1 mRNA levels are highly correlated with the focimatrix genes COL4A1, NID1 and -2 and HSPG2. Focimatrix may potentially regulate CYP11A1 expression, and the regulation of both may be important in follicular dominance | up |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
