Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli, genes CYP4A1, CYP4A2, CYP4A3 and CYP4A8 | Rattus norvegicus |
expressed in Escherichia coli, human gene CYP4A11 | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
arachidonic acid + NADPH + H+ + O2 | Homo sapiens | - |
20-hydroxyeicosatetraenoic acid + NADP+ + H2O | - |
? | |
additional information | Homo sapiens | 20-hydroxyeicosatetraenoic acid modulates renal transport activities | ? | - |
? | |
n-alkane + NAD(P)H + H+ + O2 | Homo sapiens | - |
n-alkanol + NAD(P)+ + H2O | - |
? | |
n-alkane + NAD(P)H + H+ + O2 | Rattus norvegicus | - |
n-alkanol + NAD(P)+ + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
renal cortex | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
arachidonic acid + NAD(P)H + H+ + O2 | - |
Homo sapiens | 20-hydroxyicosa-5,8,11,14-tetraenoic acid + NAD(P)+ + H2O | - |
? | |
arachidonic acid + NAD(P)H + H+ + O2 | - |
Rattus norvegicus | 20-hydroxyicosa-5,8,11,14-tetraenoic acid + NAD(P)+ + H2O | - |
? | |
arachidonic acid + NADPH + H+ + O2 | - |
Homo sapiens | 20-hydroxyeicosatetraenoic acid + NADP+ + H2O | - |
? | |
fatty acid + NAD(P)H + H+ + O2 | chain length C12-C16, arachidonic acid and oleic acid | Homo sapiens | omega-hydroxy fatty acid + NAD(P)+ + H2O | - |
? | |
fatty acid + NAD(P)H + H+ + O2 | chain length C12-C16, arachidonic acid and oleic acid | Rattus norvegicus | omega-hydroxy fatty acid + NAD(P)+ + H2O | - |
? | |
lauric acid + NAD(P)H + H+ + O2 | - |
Homo sapiens | 12-hydroxydodecanoic acid + NAD(P)+ + H2O | - |
? | |
lauric acid + NAD(P)H + H+ + O2 | - |
Rattus norvegicus | 12-hydroxydodecanoic acid + NAD(P)+ + H2O | - |
? | |
additional information | 20-hydroxyeicosatetraenoic acid modulates renal transport activities | Homo sapiens | ? | - |
? | |
n-alkane + NAD(P)H + H+ + O2 | - |
Homo sapiens | n-alkanol + NAD(P)+ + H2O | - |
? | |
n-alkane + NAD(P)H + H+ + O2 | - |
Rattus norvegicus | n-alkanol + NAD(P)+ + H2O | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Homo sapiens |