Activating Compound | Comment | Organism | Structure |
---|---|---|---|
dilauroylphosphatidylcholine | needs detergent | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli , human gene CYP4AII | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
arachidonic acid + NADPH + H+ + O2 | Homo sapiens | - |
20-hydroxyeicosatetraenoic acid + NADP+ + H2O | - |
? | |
n-alkane + NAD(P)H + H+ + O2 | Homo sapiens | - |
n-alkanol + NAD(P)+ + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
renal cortex | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(n-1)-alkanoate + NADPH + H+ + O2 | - |
Homo sapiens | (omega-1)-hydroxy-n-alkanoate + NADP+ + H2O | - |
? | |
arachidonic acid + NAD(P)H + H+ + O2 | - |
Homo sapiens | 20-hydroxyicosa-5,8,11,14-tetraenoic acid + NAD(P)+ + H2O | - |
? | |
arachidonic acid + NADPH + H+ + O2 | - |
Homo sapiens | 20-hydroxyeicosatetraenoic acid + NADP+ + H2O | - |
? | |
fatty acid + NAD(P)H + H+ + O2 | pig liver NADPH-P450 reductase and cytochrome b5 are part of the system | Homo sapiens | omega-hydroxy fatty acid + NAD(P)+ + H2O | - |
? | |
lauric acid + NAD(P)H + H+ + O2 | - |
Homo sapiens | 12-hydroxydodecanoic acid + NAD(P)+ + H2O | - |
? | |
n-alkane + NAD(P)H + H+ + O2 | - |
Homo sapiens | n-alkanol + NAD(P)+ + H2O | - |
? | |
palmitic acid + NAD(P)H + H+ + O2 | - |
Homo sapiens | 16-hydroxyhexadecanoic acid + NAD(P)+ + H2O | - |
? | |
prostaglandin A1 + [reduced NADPH-hemoprotein reductase] + O2 | - |
Homo sapiens | ? | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay conditions | Homo sapiens |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00133 | - |
PGA1 | omega-hydroxylation | Homo sapiens | |
0.0025 | - |
arachidonic acid | (omega-1)-hydroxylation | Homo sapiens | |
0.0085 | - |
lauric acid | (omega-1)-hydroxylation | Homo sapiens | |
0.00917 | - |
arachidonic acid | omega-hydroxylation | Homo sapiens | |
0.0105 | - |
palmitic acid | (omega-1)-hydroxylation | Homo sapiens | |
0.0367 | - |
palmitic acid | omega-hydroxylation | Homo sapiens | |
0.163 | - |
lauric acid | omega-hydroxylation | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Homo sapiens |