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Literature summary for 1.14.15.18 extracted from

  • Chen, T.C.
    25-Hydroxyvitamin D-1 alpha-hydroxylase (CYP27B1) is a new class of tumor suppressor in the prostate (2008), Anticancer Res., 28, 2015-2017.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the 1alpha-OHase gene is a tumor suppressor gene responsible for the normal regulation of prostate cell growth ?
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?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
LNCaP cell epidermal growth factor does not upregulate 1alpha-OHase promoter activity in the carcinogenic prostate cells. Dysregulation of 1alpha-OHase in cancer cells may lead to the aberrant growth of prostate cancer cells Homo sapiens
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PZ-HPV-7 cell epidermal growth factor upregulates 1alpha-OHase promoter activity in the noncarcinogenic prostate cells Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the 1alpha-OHase gene is a tumor suppressor gene responsible for the normal regulation of prostate cell growth Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
1alpha-OHase
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Homo sapiens
25-hydroxyvitamin D-1 alpha-hydroxylase
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Homo sapiens
CYP27B1
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Homo sapiens