Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Oryctolagus cuniculus | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
5-cholestene-3beta,7alpha-diol + reduced adrenodoxin + O2 | Oryctolagus cuniculus | - |
5-cholestene-3alpha,7alpha,26-triol + oxidized adrenodoxin + H2O | - |
? | |
5beta-cholestane-3alpha,7alpha,12alpha-triol + reduced adrenodoxin + O2 | Oryctolagus cuniculus | - |
5beta-cholestane-3alpha,7alpha,12alpha,26-tetraol + oxidized adrenodoxin + H2O | - |
? | |
5beta-cholestane-3alpha,7alpha-diol + reduced adrenodoxin + O2 | Oryctolagus cuniculus | - |
5beta-cholestane-3alpha,7alpha,26-triol + oxidized adrenodoxin + H2O | - |
? | |
7alpha-hydroxy-4-cholesten-3-one + reduced adrenodoxin + O2 | Oryctolagus cuniculus | - |
7alpha,26-dihydroxy-4-cholesten-3-one + oxidized adrenodoxin + H2O | - |
? | |
cholesterol + reduced adrenodoxin + H+ + O2 | Oryctolagus cuniculus | - |
26-hydroxycholesterol + oxidized adrenodoxin + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Oryctolagus cuniculus | - |
male New Zealand White rabbits | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Oryctolagus cuniculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5-cholestene-3beta,7alpha-diol + reduced adrenodoxin + O2 | - |
Oryctolagus cuniculus | 5-cholestene-3alpha,7alpha,26-triol + oxidized adrenodoxin + H2O | - |
? | |
5beta-cholestane-3alpha,7alpha,12alpha-triol + reduced adrenodoxin + O2 | - |
Oryctolagus cuniculus | 5beta-cholestane-3alpha,7alpha,12alpha,26-tetraol + oxidized adrenodoxin + H2O | - |
? | |
5beta-cholestane-3alpha,7alpha-diol + reduced adrenodoxin + O2 | - |
Oryctolagus cuniculus | 5beta-cholestane-3alpha,7alpha,26-triol + oxidized adrenodoxin + H2O | - |
? | |
7alpha-hydroxy-4-cholesten-3-one + reduced adrenodoxin + O2 | - |
Oryctolagus cuniculus | 7alpha,26-dihydroxy-4-cholesten-3-one + oxidized adrenodoxin + H2O | - |
? | |
cholesterol + reduced adrenodoxin + H+ + O2 | - |
Oryctolagus cuniculus | 26-hydroxycholesterol + oxidized adrenodoxin + H2O | - |
? | |
additional information | the enzyme does not perform 7alpha-, 12alpha-, or 25-hydroxylations on C27-steroids | Oryctolagus cuniculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CYP27A | - |
Oryctolagus cuniculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Oryctolagus cuniculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
Ferredoxin | - |
Oryctolagus cuniculus | |
NADPH | - |
Oryctolagus cuniculus |