BRENDA - Enzyme Database show
show all sequences of 1.14.15.11

Regioselective hydroxylation of daidzein using P450 (CYP105D7) from Streptomyces avermitilis MA4680

Pandey, B.P.; Roh, C.; Choi, K.Y.; Lee, N.; Kim, E.J.; Ko, S.; Kim, T.; Yun, H.; Kim, B.G.; Biotechnol. Bioeng. 105, 697-704 (2010)

Data extracted from this reference:

Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Streptomyces avermitilis
Q825I8
-
-
Streptomyces avermitilis MA-4680
Q825I8
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
additional information
enzyme additionally catalyzes the hydroxylation of daidzein to 7,3',4'-trihydroxyisoflavone with apparent Km and kcat values for daidzein of 21.83 mM and 15.01 per min in the presence of putidaredoxin and putidaredoxin reductase, respectively
719135
Streptomyces avermitilis
?
-
-
-
-
additional information
enzyme additionally catalyzes the hydroxylation of daidzein to 7,3',4'-trihydroxyisoflavone with apparent Km and kcat values for daidzein of 21.83 mM and 15.01 per min in the presence of putidaredoxin and putidaredoxin reductase, respectively
719135
Streptomyces avermitilis MA-4680
?
-
-
-
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
additional information
enzyme additionally catalyzes the hydroxylation of daidzein to 7,3',4'-trihydroxyisoflavone with apparent Km and kcat values for daidzein of 21.83 mM and 15.01 per min in the presence of putidaredoxin and putidaredoxin reductase, respectively
719135
Streptomyces avermitilis
?
-
-
-
-
additional information
enzyme additionally catalyzes the hydroxylation of daidzein to 7,3',4'-trihydroxyisoflavone with apparent Km and kcat values for daidzein of 21.83 mM and 15.01 per min in the presence of putidaredoxin and putidaredoxin reductase, respectively
719135
Streptomyces avermitilis MA-4680
?
-
-
-
-
Other publictions for EC 1.14.15.11
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
745541
Yao
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27
956-964
2017
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1
1
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2
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1
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2
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2
2
744146
Xu
Structural basis for the 4'-h ...
Streptomyces avermitilis, Streptomyces avermitilis DSM 46492
Appl. Microbiol. Biotechnol.
99
3081-3091
2015
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1
1
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1
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5
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4
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719674
Takamatsu
Pentalenic acid is a shunt met ...
Streptomyces avermitilis
J. Antibiot.
64
65-71
2011
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1
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1
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4
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2
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1
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1
1
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719135
Pandey
Regioselective hydroxylation o ...
Streptomyces avermitilis, Streptomyces avermitilis MA-4680
Biotechnol. Bioeng.
105
697-704
2010
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5
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