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Literature summary for 1.14.15.1 extracted from

  • Altun, A.; Guallar, V.; Friesner, R.A.; Shaik, S.; Thiel, W.
    The effect of heme environment on the hydrogen abstraction reaction of camphor in P450cam catalysis: a QM/MM study (2006), J. Am. Chem. Soc., 128, 3924-3925.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.14.15.1

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information combined quantum mechanical/molecular mechanical study, molecular dynamics, overview Pseudomonas putida

Metals/Ions

Metals/Ions Comment Organism Structure
Iron a pentacoordinated ferric P450cam complex Pseudomonas putida

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(+)-camphor + O2 + reduced putidaredoxin Pseudomonas putida
-
 (+)-exo-5-hydroxycamphor + oxidized putidaredoxin + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Pseudomonas putida P00183
-
-

Reaction

Reaction Comment Organism Reaction ID
(+)-camphor + reduced putidaredoxin + O2 = (+)-exo-5-hydroxycamphor + oxidized putidaredoxin + H2O rebound mechanism of C-H hydroxylation by P450, molecular dynamics Pseudomonas putida
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(+)-camphor + O2 + reduced putidaredoxin
-
 Pseudomonas putida (+)-exo-5-hydroxycamphor + oxidized putidaredoxin + H2O
-
 ?
(+)-camphor + O2 + reduced putidaredoxin regio- and stereoselective C-H bond hydroxylation, rebound mechanism, overview Pseudomonas putida (+)-exo-5-hydroxycamphor + oxidized putidaredoxin + H2O
-
 ?
additional information effects of heme environment on the hydrogen abstraction reaction of camphor in catalysis, overview Pseudomonas putida ?
-
 ?

Synonyms

Synonyms Comment Organism
P450cam
-
 Pseudomonas putida

Cofactor

Cofactor Comment Organism Structure
putidaredoxin
-
 Pseudomonas putida