Inhibitors | Comment | Organism | Structure |
---|---|---|---|
CO | - |
Eschscholzia californica | |
cytochrome c | - |
Eschscholzia californica | |
ketoconazole | - |
Eschscholzia californica | |
Metyrapone | - |
Eschscholzia californica | |
Prochloraz | - |
Eschscholzia californica |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.002 | - |
protopine | - |
Eschscholzia californica |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Eschscholzia lobbii | - |
- |
microsome | - |
Chelidonium majus | - |
- |
microsome | - |
Fumaria parviflora | - |
- |
microsome | - |
Dicentra cucullaria | - |
- |
microsome | membrane-bound | Eschscholzia californica | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Eschscholzia californica | the enzyme is specifically present in different plant species that produce benzo[c]phenanthridine alkaloids in culture | ? | - |
? | |
additional information | Eschscholzia lobbii | the enzyme is specifically present in different plant species that produce benzo[c]phenanthridine alkaloids in culture | ? | - |
? | |
additional information | Chelidonium majus | the enzyme is specifically present in different plant species that produce benzo[c]phenanthridine alkaloids in culture | ? | - |
? | |
additional information | Fumaria parviflora | the enzyme is specifically present in different plant species that produce benzo[c]phenanthridine alkaloids in culture | ? | - |
? | |
additional information | Dicentra cucullaria | the enzyme is specifically present in different plant species that produce benzo[c]phenanthridine alkaloids in culture | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Chelidonium majus | - |
- |
- |
Dicentra cucullaria | - |
- |
- |
Eschscholzia californica | - |
strain AST, strain BB, strain ROT | - |
Eschscholzia lobbii | - |
- |
- |
Fumaria parviflora | - |
- |
- |
no activity in Berberis stolonifera | - |
elicited and non-elicited cells | - |
no activity in Catharanthus roseus | - |
elicited and non-elicited cells | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cell suspension culture | weak activity in non-elicited cells, higher activity in elicited cells | Eschscholzia californica | - |
cell suspension culture | weak activity in non-elicited cells, higher activity in elicited cells | Eschscholzia lobbii | - |
cell suspension culture | weak activity in non-elicited cells, higher activity in elicited cells | Chelidonium majus | - |
cell suspension culture | weak activity in non-elicited cells, higher activity in elicited cells | Fumaria parviflora | - |
cell suspension culture | weak activity in non-elicited cells, higher activity in elicited cells | Dicentra cucullaria | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme is specifically present in different plant species that produce benzo[c]phenanthridine alkaloids in culture | Eschscholzia californica | ? | - |
? | |
additional information | the enzyme is specifically present in different plant species that produce benzo[c]phenanthridine alkaloids in culture | Eschscholzia lobbii | ? | - |
? | |
additional information | the enzyme is specifically present in different plant species that produce benzo[c]phenanthridine alkaloids in culture | Chelidonium majus | ? | - |
? | |
additional information | the enzyme is specifically present in different plant species that produce benzo[c]phenanthridine alkaloids in culture | Fumaria parviflora | ? | - |
? | |
additional information | the enzyme is specifically present in different plant species that produce benzo[c]phenanthridine alkaloids in culture | Dicentra cucullaria | ? | - |
? | |
protopine + [reduced NADPH-hemoprotein reductase] + O2 | - |
Eschscholzia californica | dihydrosanguinarine + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
protopine + [reduced NADPH-hemoprotein reductase] + O2 | - |
Eschscholzia lobbii | dihydrosanguinarine + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
protopine + [reduced NADPH-hemoprotein reductase] + O2 | - |
Chelidonium majus | dihydrosanguinarine + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
protopine + [reduced NADPH-hemoprotein reductase] + O2 | - |
Fumaria parviflora | dihydrosanguinarine + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
protopine + [reduced NADPH-hemoprotein reductase] + O2 | - |
Dicentra cucullaria | dihydrosanguinarine + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
- |
Eschscholzia californica |
Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
---|---|---|---|
10 | 40 | about 50% of maximal activity at 10°C and 40°C | Eschscholzia californica |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
- |
Eschscholzia californica |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6.3 | 8.5 | pH 6.3: about 35% of maximal activity, pH 8.5: about 40% of maximal activity | Eschscholzia californica |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
cytochrome P450 | the enzyme is linked to cytochrome P-450 | Eschscholzia californica |