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Literature summary for 1.14.14.91 extracted from
- The isolation and functional characterization of three liverwort genes encoding cinnamate 4-hydroxylase (2017), Plant Physiol. Biochem., 117, 42-50 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression vector and yeast strain WAT11 | Marchantia paleacea |
| expression vector and yeast strain WAT11 | Plagiochasma appendiculatum |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.000699 | - |
trans-cinnamate | 30°C, pH 7.5 | Marchantia paleacea |  |
| 0.001573 | - |
trans-cinnamate | 30°C, pH 7.5 | Marchantia paleacea | |
| 0.001747 | - |
trans-cinnamate | 30°C, pH 7.5 | Plagiochasma appendiculatum | |
| 0.01191 | - |
3-hydroxycinnamate | 30°C, pH 7.5 | Plagiochasma appendiculatum | |
| 0.01597 | - |
3-hydroxycinnamate | 30°C, pH 7.5 | Marchantia paleacea | |
| 0.2949 | - |
3-hydroxycinnamate | 30°C, pH 7.5 | Marchantia paleacea | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 57290 | - |
calculated from sequence | Marchantia paleacea |
| 59600 | - |
calculated from sequence | Marchantia paleacea |
| 61050 | - |
calculated from sequence | Plagiochasma appendiculatum |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| trans-cinnamate + [reduced NADPH-hemoprotein reductase] + O2 | Marchantia paleacea | the enzyme catalyzes the second step in phenylpropanoid synthesis, a pathway responsible for the synthesis of a wide variety of secondary metabolites | 4-hydroxycinnamate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
| trans-cinnamate + [reduced NADPH-hemoprotein reductase] + O2 | Plagiochasma appendiculatum | the enzyme catalyzes the second step in phenylpropanoid synthesis, a pathway responsible for the synthesis of a wide variety of secondary metabolites | 4-hydroxycinnamate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Marchantia paleacea | A0A1Z2R7G7 | - |
- |
| Marchantia paleacea | A0A1Z2R7G9 | - |
- |
| Plagiochasma appendiculatum | A0A1Z2R7G8 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| thallus | - |
Marchantia paleacea | - |
| thallus | - |
Plagiochasma appendiculatum | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3-hydroxycinnamate + [reduced NADPH-hemoprotein reductase] + O2 | - |
Marchantia paleacea | caffeate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
| 3-hydroxycinnamate + [reduced NADPH-hemoprotein reductase] + O2 | - |
Plagiochasma appendiculatum | caffeate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
| additional information | no activity with p-coumaric acid, 2-hydroxycinnamic acid or benzoic acid | Marchantia paleacea | ? | - |
? | |
| additional information | no activity with p-coumaric acid, 2-hydroxycinnamic acid or benzoic acid | Plagiochasma appendiculatum | ? | - |
? | |
| trans-cinnamate + [reduced NADPH-hemoprotein reductase] + O2 | - |
Marchantia paleacea | 4-hydroxycinnamate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
| trans-cinnamate + [reduced NADPH-hemoprotein reductase] + O2 | - |
Plagiochasma appendiculatum | 4-hydroxycinnamate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
| trans-cinnamate + [reduced NADPH-hemoprotein reductase] + O2 | the enzyme catalyzes the second step in phenylpropanoid synthesis, a pathway responsible for the synthesis of a wide variety of secondary metabolites | Marchantia paleacea | 4-hydroxycinnamate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
| trans-cinnamate + [reduced NADPH-hemoprotein reductase] + O2 | the enzyme catalyzes the second step in phenylpropanoid synthesis, a pathway responsible for the synthesis of a wide variety of secondary metabolites | Plagiochasma appendiculatum | 4-hydroxycinnamate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| C4H1 | - |
Marchantia paleacea |
| C4H2 | - |
Marchantia paleacea |
| MpC4H1 | - |
Marchantia paleacea |
| MpC4H2 | - |
Marchantia paleacea |
| PaC4H | - |
Plagiochasma appendiculatum |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| cytochrome P450 | a heme-thiolate protein (P-450) | Marchantia paleacea | |
| cytochrome P450 | a heme-thiolate protein (P-450) | Plagiochasma appendiculatum |
pI Value
| Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|
| Plagiochasma appendiculatum | calculated from sequence | - |
8.61 |
| Marchantia paleacea | calculated from sequence | - |
8.74 |
| Marchantia paleacea | calculated from sequence | - |
9.48 |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Plagiochasma appendiculatum | the expression level of is enhanced after treatment with abiotic stress inducers, UV irradiation or salicylic acid in the thallus of Plagiochasma appendiculatum | up |
General Information
| General Information | Comment | Organism |
|---|---|---|
| metabolism | the enzyme catalyzes the second step in phenylpropanoid synthesis, a pathway responsible for the synthesis of a wide variety of secondary metabolites | Marchantia paleacea |
| metabolism | the enzyme catalyzes the second step in phenylpropanoid synthesis, a pathway responsible for the synthesis of a wide variety of secondary metabolites | Plagiochasma appendiculatum |
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Release 2023.1 (January 2023)
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