Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.14.14.89 extracted from

  • Akashi, T.; Aoki, T.; Ayabe, S.I.
    CYP81E1, a cytochrome P450 cDNA of licorice (Glycyrrhiza echinata L.), encodes isoflavone 2'-hydroxylase (1998), Biochem. Biophys. Res. Commun., 251, 67-70.
    View publication on PubMed
Search for more literature for 1.14.14.89

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Saccharomyces cerevisae overexpressing CYP81E1 Glycyrrhiza echinata

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Glycyrrhiza echinata
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
formononetin + [reduced NADPH-hemoprotein reductase] + O2 Glycyrrhiza echinata cytochrome P450-dependent monooxygenase 2'-hydroxyformononetin + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ir

Organism

Organism UniProt Comment Textmining
Glycyrrhiza echinata
-
 elicitor-induced
-

Source Tissue

Source Tissue Comment Organism Textmining
cell suspension culture
-
 Glycyrrhiza echinata
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
daidzein + [reduced NADPH-hemoprotein reductase] + O2
-
 Glycyrrhiza echinata 2'-hydroxydaidzein + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ir
formononetin + [reduced NADPH-hemoprotein reductase] + O2
-
 Glycyrrhiza echinata 2'-hydroxyformononetin + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ir
formononetin + [reduced NADPH-hemoprotein reductase] + O2 cytochrome P450-dependent monooxygenase Glycyrrhiza echinata 2'-hydroxyformononetin + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ir
genistein + [reduced NADPH-hemoprotein reductase] + O2
-
 Glycyrrhiza echinata 2'-hydroxygenistein + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ir
additional information no substrates are 5,7,4'-trihydroxyflavone, 7,4'-dihydroxyflavone, trans-cinnamic acid and 4-coumaric acid Glycyrrhiza echinata ?
-
 ?