Literature summary for 1.14.14.79 extracted from

Harmon, S.D.; Fang, X.; Kaduce, T.L.; Hu, S.; Raj Gopal, V.; Falck, J.R.; Spector, A.A.
Oxygenation of omega-3 fatty acids by human cytochrome P450 4F3B: effect on 20-hydroxyeicosatetraenoic acid production (2006), Prostaglandins Leukot. Essent. Fatty Acids, 75, 169-177.

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Inhibitors

Inhibitors	Comment	Organism	Structure
docosahexaenoic acid	inhibitory to reaction of arachidonic acid	Homo sapiens
eicosapentaenoic acid	inhibitory to reaction of arachidonic acid	Homo sapiens
omega-3 docosapentaenoic acid	inhibitory to reaction of arachidonic acid	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q08477	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
arachidonic acid + [reduced NADPH-hemoprotein reductase] + O2	-	Homo sapiens	20-hydroxyarachidonic acid + [oxidized NADPH-hemoprotein reductase] + H2O	-	?
docosapentaenoic acid + [reduced NADPH-hemoprotein reductase] + O2	-	Homo sapiens	22-hydroxydocosapentaenoic acid + [oxidized NADPH-hemoprotein reductase] + H2O	-	?
eicosapentaenoic acid + NADPH + H+ + O2	-	Homo sapiens	20-hydroxyeicosapentaenoic acid + NADP+ + H2O	-	?

Synonyms

Synonyms	Comment	Organism
CYP4F3B	-	Homo sapiens

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Release 2023.1 (January 2023)