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Literature summary for 1.14.14.78 extracted from

  • Dhar, M.; Sepkovic, D.W.; Hirani, V.; Magnusson, R.P.; Lasker, J.M.
    Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11 (2008), J. Lipid Res., 49, 612-624.
    View publication on PubMed
Search for more literature for 1.14.14.78

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.055
-
 3-hydroxystearate in 100 mM potassium phosphate buffer (pH 7.4), at 37°C Homo sapiens
0.0564
-
 3-hydroxypalmitate in 100 mM potassium phosphate buffer (pH 7.4), at 37°C Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
phylloquinone + [reduced NADPH-hemoprotein reductase] + O2 Homo sapiens
-
 omega-hydroxyphylloquinone + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-hydroxypalmitate + [reduced NADPH-hemoprotein reductase] + O2
-
 Homo sapiens 3,16-dihydroxypalmitate + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
3-hydroxystearate + [reduced NADPH-hemoprotein reductase] + O2
-
 Homo sapiens 3,18-dihydroxystearate + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
phylloquinone + [reduced NADPH-hemoprotein reductase] + O2
-
 Homo sapiens omega-hydroxyphylloquinone + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Synonyms

Synonyms Comment Organism
CYP4F11
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Homo sapiens