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Literature summary for 1.14.14.73 extracted from

  • Souhaili-El Amri, H.; Mothe, O.; Totis, M.; Masson, C.; Batt, A.M.; Delatour, P.; Siest, G.
    Albendazole sulfonation by rat liver cytochrome P-450c (1988), J. Pharmacol. Exp. Ther., 246, 758-764 .
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
bile in bile of albendazole-treated animals, only albendazole S-oxide, but not the sulfone, is present Rattus norvegicus
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liver
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Rattus norvegicus
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Expression

Organism Comment Expression
Rattus norvegicus cytochrome P-450c is induced potently in vivo by albendazole up

General Information

General Information Comment Organism
physiological function in liver perfusion fluid of albendazole-treated animals, the concentration of albendazole-sulfoxide remains unchanged, as compared to control animals, whereas albendazole-sulfone is increased in treated animals Rattus norvegicus