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Literature summary for 1.14.14.55 extracted from
- Ontogeny of hepatic microsomal 3-hydroxylation of quinine in Adelie Penguins (2004), Comp. Biochem. Physiol. C, 138, 53-58 .
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 2-naphthoflavone | about 20% inhibition at 0.05 mM | Pygoscelis adeliae |  |
| midazolam | about 75% inhibition at 0.05 mM | Pygoscelis adeliae | |
| troleandomycin | about 10% inhibition at 0.05 mM | Pygoscelis adeliae | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Pygoscelis adeliae | - |
- |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| quinine + [reduced NADPH-hemoprotein reductase] + O2 | Pygoscelis adeliae | - |
3-hydroxyquinine + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pygoscelis adeliae | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Pygoscelis adeliae | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| quinine + [reduced NADPH-hemoprotein reductase] + O2 | - |
Pygoscelis adeliae | 3-hydroxyquinine + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CYP3A4 | - |
Pygoscelis adeliae |
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Release 2023.1 (January 2023)
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