Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.14.14.19 extracted from

  • Chen, Y.; Saini, S.; Zaman, M.S.; Hirata, H.; Shahryari, V.; Deng, G.; Dahiya, R.
    Cytochrome P450 17 (CYP17) is involved in endometrial cancinogenesis through apoptosis and invasion pathways (2011), Mol. Carcinog., 50, 16-23.
    View publication on PubMed
Search for more literature for 1.14.14.19

Protein Variants

Protein Variants Comment Organism
additional information knockdown of CYP17 by siRNA Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 gene CYP17
-

Source Tissue

Source Tissue Comment Organism Textmining
endometrial cancer cell
-
 Homo sapiens
-
HEC-1-B cell
-
 Homo sapiens
-
Ishikawa cell
-
 Homo sapiens
-
KLE cell
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
17alpha-hydroxylase
-
 Homo sapiens
CYP17
-
 Homo sapiens
cytochrome P450 17
-
 Homo sapiens
cytochrome P450c17alpha
-
 Homo sapiens

General Information

General Information Comment Organism
additional information knockdown of CYP17 by siRNA affects cellular proliferation Homo sapiens
physiological function CYP17 is involved in endometrial cancinogenesis through apoptosis and invasion pathways. CYP17 affects endometrial carcinoma KLE cell apoptosis by regulating expression of several apoptosis related genes, overview Homo sapiens