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Literature summary for 1.14.14.18 extracted from

  • Chen, N.; Shao, W.; Lv, P.; Zhang, S.; Chen, Y.; Zhu, L.; Lu, Y.; Shen, Y.
    Hemin-induced Erk1/2 activation and heme oxygenase-1 expression in human umbilical vein endothelial cells (2007), Free Radic. Res., 41, 990-996.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information hemin induces heme oxygenase-1 expression in human umbilical vein endothelial cells Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
quantitative enzyme expression analysis Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
Zn(II) protoporphyrin IX i.e. ZnPP Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
heme + AH2 + O2 Homo sapiens biliverdin is involved in hemin degradation biliverdin + Fe2+ + CO + A + H2O
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens P09601
-
-

Source Tissue

Source Tissue Comment Organism Textmining
endothelial cell
-
Homo sapiens
-
HUVEC cell i.e. human umbilical vein endothelial cell Homo sapiens
-
umbilical vein
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
heme + AH2 + O2
-
Homo sapiens biliverdin + Fe2+ + CO + A + H2O
-
?
heme + AH2 + O2 biliverdin is involved in hemin degradation Homo sapiens biliverdin + Fe2+ + CO + A + H2O
-
?

Synonyms

Synonyms Comment Organism
heme oxygenase-1
-
Homo sapiens
HO-1
-
Homo sapiens