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Literature summary for 1.14.14.176 extracted from

  • Edgar, S.; Li, F.S.; Qiao, K.; Weng, J.K.; Stephanopoulos, G.
    Engineering of taxadiene synthase for improved selectivity and yield of a key taxol biosynthetic intermediate (2017), ACS Synth. Biol., 6, 201-205 .
    View publication on PubMed
Search for more literature for 1.14.14.176

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
taxa-4(20)-11(12)-diene + AH2 + O2 Taxus sp.
-
 ?
-
 ?
taxa-4,11-diene + [reduced NADPH-hemoprotein reductase] + O2 Taxus sp.
-
 taxa-4(20),11(12)-dien-5alpha-ol + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Taxus sp.
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
taxa-4(20)-11(12)-diene + AH2 + O2
-
 Taxus sp. ?
-
 ?
taxa-4,11-diene + [reduced NADPH-hemoprotein reductase] + O2
-
 Taxus sp. taxa-4(20),11(12)-dien-5alpha-ol + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Synonyms

Synonyms Comment Organism
CYP725A4
-
 Taxus sp.
taxadien-5alpha-hydroxylase
-
 Taxus sp.
taxadiene synthase
-
 Taxus sp.