Literature summary for 1.14.14.17 extracted from

Zhang, D.H.; Jiang, L.X.; Li, N.; Yu, X.; Zhao, P.; Li, T.; Xu, J.W.
Overexpression of the squalene epoxidase gene alone and in combination with the 3-hydroxy-3-methylglutaryl coenzyme A gene increases ganoderic acid production in Ganoderma lingzhi (2017), J. Agric. Food Chem., 65, 4683-4690 .

Search for more literature for 1.14.14.17

Application

Application	Comment	Organism
synthesis	simultaneous overexpression of squalene epoxidase and 3-hydroxy-3-methylglutaryl coenzyme A enhances individual ganoderic acid production. The overexpressing strain produces maximum ganoderic acid-T, ganoderic acid-S, ganoderic acid-Mk, and ganoderic acid-Me contents of 90.4, 35.9, 6.2, and 61.8 microg/100 mg dry weight, respectively	Ganoderma lucidum

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Ganoderma lucidum	Ganoderma lucidum

Organism

Organism	UniProt	Comment	Textmining
Ganoderma lucidum	A0A1Y0JYI5	-	-

Synonyms

Synonyms	Comment	Organism
squalene epoxidase	-	Ganoderma lucidum

General Information

General Information	Comment	Organism
physiological function	squalene epoxidase overexpression upregulates lanosterol synthase gene expression in the biosynthetic pathway and stimulates ganoderic acid accumulation	Ganoderma lucidum

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)