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Literature summary for 1.14.14.17 extracted from
- Molecular cloning and characterization of the gene encoding squalene epoxidase in Panax notoginseng (2008), DNA Seq., 19, 270-273.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| DNA and amino acid sequence determination and analysis, quantitative expression analysis, phylogenetic tree | Panax notoginseng |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | membrane-associated enzyme | Panax notoginseng | 16020 | - |
| microsome | membrane-associated enzyme | Panax notoginseng | - |
- |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 59140 | - |
x * 59140, sequence calculation | Panax notoginseng |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| squalene + AH2 + O2 | Panax notoginseng | rate-limiting enzyme in the triterpene saponins biosynthetic pathway, overview | (S)-squalene-2,3-epoxide + A + H2O | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Panax notoginseng | Q1PID4 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| additional information | quantitative expression analysis | Panax notoginseng | - |
| root | high expression level in roots, especially in 3-year-old roots | Panax notoginseng | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| squalene + AH2 + O2 | - |
Panax notoginseng | (S)-squalene-2,3-epoxide + A + H2O | - |
? | |
| squalene + AH2 + O2 | rate-limiting enzyme in the triterpene saponins biosynthetic pathway, overview | Panax notoginseng | (S)-squalene-2,3-epoxide + A + H2O | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 59140, sequence calculation | Panax notoginseng |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| squalene epoxidase | - |
Panax notoginseng |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| FAD | - |
Panax notoginseng | |
| additional information | the enzyme sequence contains a Rossmann-dinucleotide binding fold and NAD(P)-binding site | Panax notoginseng |
pI Value
| Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|
| Panax notoginseng | sequence calculation | - |
8.81 |
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Release 2023.1 (January 2023)
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