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Literature summary for 1.14.14.16 extracted from

  • Rottembourg, D.; Deal, C.; Lambert, M.; Mallone, R.; Carel, J.C.; Lacroix, A.; Caillat-Zucman, S.; le Deist, F.
    21-Hydroxylase epitopes are targeted by CD8 T cells in autoimmune Addisons disease (2010), J. Autoimmun., 35, 309-315.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens P08686
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-

Synonyms

Synonyms Comment Organism
21-hydroxylase
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Homo sapiens
21OH
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Homo sapiens

General Information

General Information Comment Organism
additional information In autoimmune adrenal deficiency, autoantibodies target the 21-hydroxylase protein, 21-hydroxylase-specific T cells are CD8+ T cells. A T-cell epitope mapping study using 49 overlapping 20mer peptides covering the 21OH sequence in patients with isolated Addison's disease, Autoimmune Polyendocrine Syndrome 1 and 2 for determination of the epitopes targeted in autoimmune adrenal deficiency, detailed overview Homo sapiens