Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli | Bos taurus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Bos taurus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
17alpha-hydroxyprogesterone + NADPH + H+ + O2 | P450c21 catalyzes hydroxylation at C-21, 17alpha-hydroxyprogesterone is a better substrate for P450c21 than progesterone from the catalytic coupling with consumption of NADPH | Bos taurus | 11-deoxycortisol + NADP+ + H2O | - |
? | |
progesterone + NADPH + H+ + O2 | P450c21 catalyzes hydroxylation at C-21 | Bos taurus | 11-deoxycorticosterone + NADP+ + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
cytochrome P450 steroid 21-hydroxylase | - |
Bos taurus |
P450c21 | - |
Bos taurus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
cytochrome P450 | - |
Bos taurus | |
NADPH | - |
Bos taurus |