Literature summary for 1.14.14.154 extracted from

Song, X.; Tai, P.; Yan, J.; Xu, B.; Chen, X.; Ouyang, H.; Zhang, M.; Xia, G.
Expression and regulation of lanosterol 14alpha-demethylase in mouse embryo and uterus during the peri-implantation period (2008), Reprod. Fertil. Dev., 20, 964-972.

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Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	progesterone treatment does not induce expression in the uterus of ovariectomised mice	Mus musculus
oestrogen	induces a high level of LDM expression in the uterus of ovariectomised mice	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
embryo	is selectively expressed in preimplantation embryos	Mus musculus	-
uterus	during the peri-implantation period, is selectively expressed in the uterine subluminal stroma surrounding the implanting blastocyst on day 5 of pregnancy. High level of LDM expression in the uterus decidua on days 6-8 of pregnancy. Is absent in the uterus on day 5 of pseudopregnancy	Mus musculus	-

Synonyms

Synonyms	Comment	Organism
lanosterol 14alpha-demethylase	-	Mus musculus
LDM	-	Mus musculus

Expression

Organism	Comment	Expression
Mus musculus	LDM expression is induced in the uterine stroma under artificial decidualisation. Oestrogen, but not progesterone, treatment induces a high level of LDM expression in the uterus of ovariectomised mice	up

General Information

General Information	Comment	Organism
physiological function	LDM is closely related to mouse embryo implantation and can be upregulated by oestrogen	Mus musculus

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Release 2023.1 (January 2023)