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Literature summary for 1.14.14.154 extracted from

  • Buckner, F.S.; Joubert, B.M.; Boyle, S.M.; Eastman, R.T.; Verlinde, C.L.; Matsuda, S.P.
    Cloning and analysis of Trypanosoma cruzi lanosterol 14alpha-demethylase (2003), Mol. Biochem. Parasitol., 132, 75-81.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression of gene during both insect and mammalian life-cycle stage Trypanosoma cruzi

Protein Variants

Protein Variants Comment Organism
additional information enzyme is able to complement the function of the homologous gene in yeast Trypanosoma cruzi

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
52000
-
x * 52000, SDS-PAGE, recombinant enzyme Trypanosoma cruzi

Organism

Organism UniProt Comment Textmining
Trypanosoma cruzi
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
lanosterol + [reduced NADPH-hemoprotein reductase] + O2
-
Trypanosoma cruzi 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + [oxidized NADPH-hemoprotein reductase] + H2O
-
?

Subunits

Subunits Comment Organism
? x * 52000, SDS-PAGE, recombinant enzyme Trypanosoma cruzi

Cofactor

Cofactor Comment Organism Structure
cytochrome P450
-
Trypanosoma cruzi