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Literature summary for 1.14.14.141 extracted from

  • Larbat, R.; Hehn, A.; Hans, J.; Schneider, S.; Jugde, H.; Schneider, B.; Matern, U.; Bourgaud, F.
    Isolation and functional characterization of CYP71AJ4 encoding for the first P450 monooxygenase of angular furanocoumarin biosynthesis (2009), J. Biol. Chem., 284, 4776-4785.
    View publication on PubMed
Search for more literature for 1.14.14.141

Cloned(Commentary)

Cloned (Comment) Organism
expressed in yeast strain WAT 11 Apium graveolens
expressed in yeast strain WAT 11 Pastinaca sativa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00054
-
 (+)-marmesin
-
 Apium graveolens
0.0013
-
 (+)-marmesin
-
 Pastinaca sativa
0.019
-
 5-hydroxymarmesin
-
 Pastinaca sativa
0.054
-
 5-hydroxymarmesin
-
 Apium graveolens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5-hydroxymarmesin + [reduced NADPH-hemoprotein reductase] + O2 Apium graveolens
-
 bergaptol + acetone + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
5-hydroxymarmesin + [reduced NADPH-hemoprotein reductase] + O2 Pastinaca sativa
-
 bergaptol + acetone + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Apium graveolens C0SJS4
-
-
Pastinaca sativa C0SJS2
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(+)-marmesin + [reduced NADPH-hemoprotein reductase] + O2
-
 Apium graveolens psoralen + [oxidized NADPH-hemoprotein reductase] + acetone + 2 H2O
-
 ?
(+)-marmesin + [reduced NADPH-hemoprotein reductase] + O2
-
 Pastinaca sativa psoralen + [oxidized NADPH-hemoprotein reductase] + acetone + 2 H2O
-
 ?
5-hydroxymarmesin + [reduced NADPH-hemoprotein reductase] + O2
-
 Apium graveolens bergaptol + acetone + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
5-hydroxymarmesin + [reduced NADPH-hemoprotein reductase] + O2
-
 Pastinaca sativa bergaptol + acetone + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Synonyms

Synonyms Comment Organism
CYP71AJ2
-
 Apium graveolens
CYP71AJ3
-
 Pastinaca sativa
psoralen synthase
-
 Apium graveolens
psoralen synthase
-
 Pastinaca sativa