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Literature summary for 1.14.14.14 extracted from

  • Mills, L.J.; Gutjahr-Gobell, R.E.; Zaroogian, G.E.; Horowitz, D.B.; Laws, S.C.
    Modulation of aromatase activity as a mode of action for endocrine disrupting chemicals in a marine fish (2014), Aquat. Toxicol., 147, 140-150 .
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
1,4,6-androstatriene-3,17-dione treatment with the aromatase inhibitor ATD results in significantly decreased aromatase activity in male and female brain,but has no significant impact on ovarian aromatase activity Tautogolabrus adspersus

Organism

Organism UniProt Comment Textmining
Tautogolabrus adspersus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
brain male brain aromatase activity is signficantly increased by treatments with estradiol or ethynylestradiol while female brain aromatase activity is unaffected Tautogolabrus adspersus
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gonad
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Tautogolabrus adspersus
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ovary ovarian aromatase activity is significantly decreased by treatments with estradiol or ethynylestradiol Tautogolabrus adspersus
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General Information

General Information Comment Organism
physiological function a decrease or an increase in male brain aromatase activity relative to controls is associated with decreased egg production and is also correlated with significant changes in gonadosomatic index in both sexes Tautogolabrus adspersus