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Literature summary for 1.14.14.127 extracted from

  • Pratt, G.; Jennings, R.; Weaver, R.
    The influence of a P450 inhibitor on methyl farnesoate levels in cockroach corpora allata, in vitro (1984), Insect Biochem., 14, 609-614.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
methyl (2E,6E)-3,7-dimethyl-8-(3,4-methylenedioxyphenoxy)-octadienoate inhibits juvenile hormone biosynthesis in vitro by spontaneously active glands, presumably by direct inhibition of the epoxidase, and also inhibits the production of total methyl ester Periplaneta americana

Organism

Organism UniProt Comment Textmining
Periplaneta americana
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Source Tissue

Source Tissue Comment Organism Textmining
corpus allatum clear relationship between methyl farnesoate levels and the total rate of juvenile hormone biosynthesis in individual pairs of glands. Methyl farnesoate levels rise 30fold during the spontaneous activity cycle, but never reach a level causing saturation of the methyl farnesoate epoxidase Periplaneta americana
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