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Literature summary for 1.14.14.114 extracted from

  • Teoh, K.H.; Polichuk, D.R.; Reed, D.W.; Nowak, G.; Covello, P.S.
    Artemisia annua L. (Asteraceae) trichome-specific cDNAs reveal CYP71AV1, a cytochrome P450 with a key role in the biosynthesis of the antimalarial sesquiterpene lactone artemisinin (2006), FEBS Lett., 580, 1411-1416.
    View publication on PubMed
Search for more literature for 1.14.14.114

Cloned(Commentary)

Cloned (Comment) Organism
expression in Saccharomyces cerevisiae Artemisia annua

Organism

Organism UniProt Comment Textmining
Artemisia annua Q1PS23
-
-

Source Tissue

Source Tissue Comment Organism Textmining
flower bud moderate expression Artemisia annua
-
leaf low expression Artemisia annua
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root low expression Artemisia annua
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trichome highest expression Artemisia annua
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
amorpha-4,11-diene + [reduced NADPH-hemoprotein reductase] + O2
-
 Artemisia annua artemisinic alcohol + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
artemisinic alcohol + [reduced NADPH-hemoprotein reductase] + O2
-
 Artemisia annua artemisinic aldehyde + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
artemisinic aldehyde + [reduced NADPH-hemoprotein reductase] + O2
-
 Artemisia annua artemisinate + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
additional information no substrates: limonene, alpha-pinene, beta-pinene and pinocarveol, and the sesquiterpenes ()-alloisolongifolene, caryophyllene, ()-alpha-gurjunene, (+)-gamma-gurjunene, (+)-ledene,(+)-beta-selinene and (+)-valencene Artemisia annua ?
-
 ?

Synonyms

Synonyms Comment Organism
amorpha-4,11-diene C-12 oxidase
-
 Artemisia annua
CYP71AV1
-
 Artemisia annua