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Literature summary for 1.14.14.103 extracted from

  • Guirimand, G.; Guihur, A.; Poutrain, P.; Hericourt, F.; Mahroug, S.; St-Pierre, B.; Burlat, V.; Courdavault, V.
    Spatial organization of the vindoline biosynthetic pathway in Catharanthus roseus (2010), J. Plant Physiol., 168, 549-557.
    View publication on PubMed
Search for more literature for 1.14.14.103

Cloned(Commentary)

Cloned (Comment) Organism
DNA and amino acid sequence determination and analysis Catharanthus roseus

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
 Catharanthus roseus 5783
-
endoplasmic reticulum membrane T16H is anchored to the endoplasmic reticulum as a monomer via a putative 18-residue N-terminal helix Catharanthus roseus 5789
-
additional information vindoline biosynthesis pathway enzyme subcellular localization study, overview Catharanthus roseus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
tabersonine + NADPH + H+ + O2 Catharanthus roseus
-
 16-hydroxytabersonine + NADP+ + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Catharanthus roseus C0KYN4
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
 Catharanthus roseus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
tabersonine + NADPH + H+ + O2
-
 Catharanthus roseus 16-hydroxytabersonine + NADP+ + H2O
-
 ?

Subunits

Subunits Comment Organism
monomer
-
 Catharanthus roseus

Synonyms

Synonyms Comment Organism
CYP71D12
-
 Catharanthus roseus
T16H
-
 Catharanthus roseus
tabersonine 16-monooxygenase
-
 Catharanthus roseus

Cofactor

Cofactor Comment Organism Structure
cytochrome P450
-
 Catharanthus roseus

General Information

General Information Comment Organism
metabolism the enzyme catalyzes the first step in the biosynthesis of vindoline, which constitutes the main terpenoid indole alkaloid accumulated in leaves of Catharanthus roseus, spatial organization of the vindoline biosynthetic pathway, overview. Absence of metabolic channeling in the vindoline biosynthetic pathway. Importance of inter- and intracellular translocations of intermediates during the vindoline biosynthesis and potential regulatory role, overview Catharanthus roseus