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Literature summary for 1.14.14.1 extracted from

  • Beedanagari, S.R.; Bebenek, I.; Bui, P.; Hankinson, O.
    Resveratrol inhibits dioxin-induced expression of human CYP1A1 and CYP1B1 by inhibiting recruitment of the aryl hydrocarbon receptor complex and RNA polymerase II to the regulatory regions of the corresponding genes (2009), Toxicol. Sci., 110, 61-67.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Hep-G2 cell CYP1A1 and CYP1A2 Homo sapiens
-
MCF-7 cell CYP1A1, CYP1A2 and CYP1B1 Homo sapiens
-

Synonyms

Synonyms Comment Organism
CYP1A1
-
Homo sapiens
CYP1B1
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens resveratrol inhibits dioxin-induced expression of CYP1A1, CYP1A2 and CYP1B1 by directly or indirectly inhibiting the recruitment of the transcription factors aryl hydrocarbon receptor and aryl hydrocarbon nuclear translocator to the xenobiotic response elements of the corresponding genes down
Homo sapiens 0.0001 mM dioxin treatment for 24, 48, and 72 h induces CYP1A1, CYP1A2 and CYP1B1 mRNA levels up