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Literature summary for 1.14.14.1 extracted from

  • Henczova, M.; Deer, A.K.; Filla, A.; Komlosi, V.; Mink, J.
    Effects of Cu(2+) and Pb(2+) on different fish species: liver cytochrome P450-dependent monooxygenase activities and FTIR spectra (2008), Comp. Biochem. Physiol. C, 148, 53-60.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Cu2+ inhibits the enzyme in vitro and inactivate it in vivo, but also induce the enzyme in vivo in the first 24 h, overview Cyprinus carpio
Cu2+ inhibits the enzyme in vitro and inactivate it in vivo, but also induce the enzyme in vivo in the first 24 h, overview Hypophthalmichthys molitrix
Cu2+ inhibits the enzyme in vitro and inactivate it in vivo, but also induce the enzyme in vivo in the first 24 h, overview Silurus glanis
Pb2+ inhibits the enzyme in vitro and inactivate it in vivo, but also induce the enzyme in vivo in the first 24 h, overview Cyprinus carpio
Pb2+ inhibits the enzyme in vitro and inactivate it in vivo, but also induce the enzyme in vivo in the first 24 h, overview Hypophthalmichthys molitrix
Pb2+ inhibits the enzyme in vitro and inactivate it in vivo, but also induce the enzyme in vivo in the first 24 h, overview Silurus glanis

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
Cyprinus carpio
-
-
microsome
-
Silurus glanis
-
-
microsome
-
Hypophthalmichthys molitrix
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Fe2+
-
Cyprinus carpio
Fe2+
-
Silurus glanis
Fe2+
-
Hypophthalmichthys molitrix

Organism

Organism UniProt Comment Textmining
Cyprinus carpio
-
-
-
Hypophthalmichthys molitrix
-
-
-
Silurus glanis
-
-
-

Purification (Commentary)

Purification (Comment) Organism
native enzyme partially by microsome preparation Cyprinus carpio
native enzyme partially by microsome preparation Silurus glanis
native enzyme partially by microsome preparation Hypophthalmichthys molitrix

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Cyprinus carpio
-
liver
-
Silurus glanis
-
liver
-
Hypophthalmichthys molitrix
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Cyprinus carpio
additional information
-
-
Silurus glanis
additional information
-
-
Hypophthalmichthys molitrix

Synonyms

Synonyms Comment Organism
liver cytochrome P450-dependent monooxygenase
-
Cyprinus carpio
liver cytochrome P450-dependent monooxygenase
-
Silurus glanis
liver cytochrome P450-dependent monooxygenase
-
Hypophthalmichthys molitrix

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
assay at Cyprinus carpio
30
-
assay at Silurus glanis
30
-
assay at Hypophthalmichthys molitrix

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
assay at Cyprinus carpio
7.4
-
assay at Silurus glanis
7.4
-
assay at Hypophthalmichthys molitrix

Cofactor

Cofactor Comment Organism Structure
cytochrome P450
-
Cyprinus carpio
cytochrome P450
-
Silurus glanis
cytochrome P450
-
Hypophthalmichthys molitrix