Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | the specific enzyme activity is not affected by cloricromene in vitro and in vivo in liver and kidney | Oryctolagus cuniculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Oryctolagus cuniculus | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
kynurenine + NADPH + O2 | Oryctolagus cuniculus | the enzyme is involved in the kynurenine pathway of tryptophan metabolsim, overview | 3-hydroxy-kynurenine + NADP+ + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Oryctolagus cuniculus | - |
male, 4-month-old diabetic/hyperlipidemic New Zealand White rabbits | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Oryctolagus cuniculus | - |
liver | - |
Oryctolagus cuniculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0004 | - |
activity in kidney | Oryctolagus cuniculus |
0.001 | - |
activity in liver | Oryctolagus cuniculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
kynurenine + NADPH + O2 | - |
Oryctolagus cuniculus | 3-hydroxy-kynurenine + NADP+ + H2O | - |
? | |
kynurenine + NADPH + O2 | the enzyme is involved in the kynurenine pathway of tryptophan metabolsim, overview | Oryctolagus cuniculus | 3-hydroxy-kynurenine + NADP+ + H2O | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Oryctolagus cuniculus |