Cloned (Comment) | Organism |
---|---|
expression analysis of FMO3 in liver and after treatment with conjugated linoleic acid isomers | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | cis9, trans11-conjugated linoleic acid reduces expression of FMO3 by 61% | Mus musculus | |
trans10, cis12-conjugated linoleic acid | reduces expression of FMO3 by 95%, and inhibits activity of hepatic microsomal FMO by 40% and of isozyme FMO3 activity by 67%, the compound has a strong effect on hepatic fatyy acid oxidation, overview | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Mus musculus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | the enzyme is involved in fatty acid oxidation in the liver, as well as in drug detoxification | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
8-weeks-old female C57BL/6N mice | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | expression analysis of FMO3 in liver and after treatment with conjugated linoleic acid isomers | Mus musculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
methyl 4-tolyl sulfide + NADPH + O2 | - |
Mus musculus | methyl 4-tolyl sulfoxide + NADP+ + H2O | - |
? | |
additional information | the enzyme is involved in fatty acid oxidation in the liver, as well as in drug detoxification | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
flavin monooxygenase | - |
Mus musculus |
FMO | - |
Mus musculus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Mus musculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | 9.5 | assay at | Mus musculus |