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Literature summary for 1.14.13.7 extracted from

  • Detmer, K.; Massey, V.
    Effect of substrate and pH on the oxidative half-reaction of phenol hydroxylase (1985), J. Biol. Chem., 260, 5998-6005.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
Thiophenol binds to the enzyme and stimulates NADPH oxidation Cutaneotrichosporon cutaneum

Organism

Organism UniProt Comment Textmining
Cutaneotrichosporon cutaneum
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2,3,5,6-tetrafluorophenol + O2 + NADPH
-
Cutaneotrichosporon cutaneum 3,4,6-trifluoro-2-benzoquinone + NADP+ + F-
-
?
3-aminophenol + O2 + NADPH
-
Cutaneotrichosporon cutaneum ?
-
?
3-chlorophenol + O2 + NADPH
-
Cutaneotrichosporon cutaneum ?
-
?
3-hydroxyphenol + O2 + NADPH
-
Cutaneotrichosporon cutaneum ?
-
?
3-methylphenol + O2 + NADPH
-
Cutaneotrichosporon cutaneum ?
-
?
4-hydroxyphenol + O2 + NADPH
-
Cutaneotrichosporon cutaneum ?
-
?
phenol + NADPH + O2
-
Cutaneotrichosporon cutaneum catechol + NADP+ + H2O
-
?
thiophenol + O2 + NADPH
-
Cutaneotrichosporon cutaneum ?
-
?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
additional information
-
effect of pH on oxidative half-reaction Cutaneotrichosporon cutaneum

Cofactor

Cofactor Comment Organism Structure
NADPH
-
Cutaneotrichosporon cutaneum