BRENDA - Enzyme Database show
show all sequences of 1.14.13.40

2-Aminobenzoyl-CoA monooxygenase/reductase, a novel type of flavoenzyme. Studies on the stoichiometry and the course of the reaction

Buder, R.; Ziegler, K.; Fuchs, G.; Langkau, B.; Ghisla, S.; Eur. J. Biochem. 185, 637-643 (1989)

Data extracted from this reference:

Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Pseudomonas sp.
-
-
-
Pseudomonas sp. KB740
-
-
-
Purification (Commentary)
Commentary
Organism
apparent homogeneity
Pseudomonas sp.
Reaction
Reaction
Commentary
Organism
anthraniloyl-CoA + 2 NAD(P)H + 2 H+ + O2 = 2-amino-5-oxocyclohex-1-enecarboxyl-CoA + H2O + 2 NAD(P)+
reaction mechanism
Pseudomonas sp.
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2-aminobenzoyl-CoA + NAD(P)H + O2
-
438852
Pseudomonas sp.
2-amino-5-oxocyclohex-1-enecarboxyl-CoA + H2O + NAD(P)+
at least 2 different reaction products depending on the concentration of NADH
438852
Pseudomonas sp.
?
2-aminobenzoyl-CoA + NAD(P)H + O2
-
438852
Pseudomonas sp. KB740
2-amino-5-oxocyclohex-1-enecarboxyl-CoA + H2O + NAD(P)+
at least 2 different reaction products depending on the concentration of NADH
438852
Pseudomonas sp. KB740
?
Cofactor
Cofactor
Commentary
Organism
Structure
FAD
flavoprotein
Pseudomonas sp.
NADH
-
Pseudomonas sp.
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
FAD
flavoprotein
Pseudomonas sp.
NADH
-
Pseudomonas sp.
Purification (Commentary) (protein specific)
Commentary
Organism
apparent homogeneity
Pseudomonas sp.
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2-aminobenzoyl-CoA + NAD(P)H + O2
-
438852
Pseudomonas sp.
2-amino-5-oxocyclohex-1-enecarboxyl-CoA + H2O + NAD(P)+
at least 2 different reaction products depending on the concentration of NADH
438852
Pseudomonas sp.
?
2-aminobenzoyl-CoA + NAD(P)H + O2
-
438852
Pseudomonas sp. KB740
2-amino-5-oxocyclohex-1-enecarboxyl-CoA + H2O + NAD(P)+
at least 2 different reaction products depending on the concentration of NADH
438852
Pseudomonas sp. KB740
?
Other publictions for EC 1.14.13.40
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
744409
Bergner
Anthranoyl-CoA monooxygenase/ ...
Azoarcus evansii
Biochim. Biophys. Acta
1854
890-896
2015
-
-
1
-
-
-
-
-
-
-
1
1
-
3
-
-
-
-
-
-
-
-
2
1
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-
-
-
-
-
-
2
-
-
-
-
-
1
2
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
2
1
-
-
-
-
-
-
-
-
-
1
1
-
-
-
438855
Schuhle
Two similar gene clusters codi ...
Azoarcus evansii, Azoarcus evansii KB740
J. Bacteriol.
183
5268-5278
2001
-
-
1
-
-
-
-
-
-
-
1
-
-
4
-
-
1
-
-
-
-
-
-
-
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-
-
-
-
-
-
-
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1
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1
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1
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-
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-
-
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-
-
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-
-
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-
438856
Torres
Theoretical investigation of t ...
Azoarcus evansii
Proc. Natl. Acad. Sci. USA
96
14748-14752
1999
-
-
-
-
-
-
-
-
-
-
-
-
-
1
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-
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1
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-
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-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
438857
Langkau
2-Aminobenzoyl-CoA monooxygena ...
Pseudomonas sp., Pseudomonas sp. KB740
Eur. J. Biochem.
230
676-685
1995
-
-
-
-
-
-
-
2
-
-
-
-
-
11
-
-
1
-
-
-
1
1
6
1
-
-
2
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
1
-
-
1
1
6
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
438858
Lochmeyer
Anaerobic degradation of 2-ami ...
Pseudomonas sp., Pseudomonas sp. K172
J. Bacteriol.
174
3621-3628
1992
-
-
-
-
-
-
-
1
-
1
-
-
-
8
-
-
-
-
-
-
1
-
3
-
-
-
-
-
1
-
-
1
-
-
-
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-
1
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
1
-
3
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
438853
Langkau
2-Aminobenzoyl-CoA monooxygena ...
Pseudomonas sp.
Eur. J. Biochem.
191
365-371
1990
-
-
-
-
-
-
-
-
-
-
-
1
-
2
-
-
-
-
-
-
-
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3
-
-
-
-
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-
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-
3
-
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-
3
-
-
-
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-
-
-
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-
1
-
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-
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3
-
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-
-
-
-
-
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-
438854
Altenschmidt
Evidence that enzymes of a nov ...
Pseudomonas sp., Pseudomonas sp. KB740
Eur. J. Biochem.
194
647-653
1990
-
-
1
-
-
-
-
-
-
-
-
-
-
13
-
-
-
-
-
-
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-
4
1
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-
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-
-
1
-
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1
1
-
-
-
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-
-
-
-
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-
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4
1
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-
-
-
-
-
-
-
-
-
-
-
-
438851
Buder
2-Aminobenzoyl-CoA monooxygena ...
Pseudomonas sp., Pseudomonas sp. KB740
Eur. J. Biochem.
185
629-635
1989
-
-
-
-
-
-
5
5
-
-
2
2
-
12
-
-
1
-
-
-
1
1
8
1
-
-
1
1
1
-
-
3
-
-
-
-
-
-
3
-
-
-
-
5
-
5
-
-
2
2
-
-
-
1
-
-
1
1
8
1
-
-
1
1
1
-
-
-
-
-
-
-
-
-
438852
Buder
2-Aminobenzoyl-CoA monooxygena ...
Pseudomonas sp., Pseudomonas sp. KB740
Eur. J. Biochem.
185
637-643
1989
-
-
-
-
-
-
-
-
-
-
-
-
-
12
-
-
1
1
-
-
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
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2
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1
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2
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